Many meta-languages have been proposed for writing rule-based operational semantics, in order to provide general interpreters and analysis tools. We take a different approach. We develop a meta-language for a skeletal semantics of a language, where each skeleton describes the complete semantic behaviour of a language construct. We define a general notion of interpretation, which provides a systematic and language-independent way of deriving semantic judgements from the skeletal semantics. We provide four generic interpretations of our skeletal semantics to yield: a simple well-formedness interpretation; a concrete interpretation; an abstract interpretation; and a constraint generator for flow-sensitive analysis. We prove general consistency results, establishing that the concrete and abstract interpretations are consistent and that any solution to the constraints generated by the constraint generator must be a correct abstract semantics.